BEDOYECTA^®

Ingredients:   

Every 2 mL syringe contains:

• Hydroxocobalamin (vitamin B12) 10,000.00 mcg.
• Thiamine hydrochloride (vitamin B1) 100.00 mg.
• Pyridoxine hydrochloride (vitamin B6) 50.00 mg.
• Benzyl alcohol 0.06 mL.
• Excipient, enough to total 2.00 mL.

Indications: Antineuritic, antineuralgic.

Posology: As prescribed by the doctor.

Route of administration: Intramuscular (IM).

How to use: Slit open the bottom of the case. 2) Carefully remove the syringe. 3) Remove the rubber cap at the top of the syringe. 4) Remove the needle from its case and join it firmly to the syringe. 5) Remove the plastic cap on the needle. 6) Administer the medication. 7) For safety reasons, discard the syringe after use.

Nota: Sterility of the product cannot be guaranteed if there is any damage to the case or the syringe.

Adverse reactions: Hypersensitivity reactions: anaphylaxis, skin reactions.

Warnings: This product should only be taken under the supervision of a doctor. Do not administer during pregnancy or if pregnancy is suspected, nor while breast feeding, unless ordered by the doctor. When taking this product, urine turns yellow. Do not to exceed the prescribed dose.

Precautions:  Avoid alcoholic beverages. Care must be taken in the case of patients being treated with levodopa.

Contraindications: Allergy to nicotimanide, riboflavin (vitamin B2), allergy to any of the components of the formula.

Interactions: Barbiturates, citrates, carbonates, alcohol, neomycin, colchicine, para-aminosalicyclic acid, potassium, chloramphenicol and other bone-marrow suppression drugs may reduce bioavailability. Isoniazid, cycloserine, penicillamine, hydralazine and oral contraceptives increase the daily requirements of pyridoxine and revert the therapeutic effect of levodopa.

Storage: Store in a cool place and out of the light at less than 30º C. E.F. 29.101/17.

KEEP OUT OF THE REACH OF CHILDREN.

DO NOT DISCARD THE PACKAGING

BETADINE^® JABÓN LÍQUIDO 

Ingredients:

• 7.5% povidone-iodine with 0.75% of iodine available, together with non-ionic detergents.

Indications: Pre- and post-operative scrubbing of surgical staff. Preoperative cleaning of surgical field, of wounds and burns. For use in the doctor’s office. Adjuvant for the treatment of a variety of skin infections.

Contraindications: Hypersensitivity to iodine

Dosage Form: Bottle containing 120 ml.  E.F.15.502.

BETADINE^® SOLUCIÓN

Ingredients:

• 10% povidone-iodine with 1% of iodine available,  buffered by special buffers with a pH similar to that of normal skin..

Indications: Topical antiseptic providing coverage for a broad range of bactericide and fungicide activity, especially for pre- and post-operative preparation of the surgical field and very useful for outpatients. Treatment of wounds, burns and a variety of skin infections.

Contraindications: Hypersensitivity to iodine.

Dosage Form: Bottle with 180 ml of the solution E.F.15.503.

BONAMES^®

Ingredients :

• Monohydrate ibandronate sodium: 168.75 mg (ibandronic acid 150 mg).

Indications: Treatment of post-menopausal osteoporosis.

Dosage: 1 tablet a month.

How to use: Take on an empty stomach with approximately 8 ounces (250 ml) of water; do not eat or take medications at the same time nor during the first hour after taking the medication. Remain upright for one hour after taking the medication. Do not chew.

Adverse reactions: Flu-like symptoms (fever, headache, myalgia, pain in bones). Elevated liver enzymes, hypocalcemia, hypophosphatemia and hypomagnesemia, esophagitis, gastritis. Use with caution in the case of a history of gastric ulcers.

Warnings: Do not administer during pregnancy or suspected pregnancy nor when breastfeeding. This product should not be taken by patients who are lactose or galactose intolerant.

Dosage Form: Coated pill: Box with 1. E.F. 37.009.

BRASARTAN^®

Ingredients :

• Valsartan, 80 and 160 mg tablets.

Indications: Treatment of mild to moderate arterial hypertension. Treatment of heart failure, stages II to IV.

Dosage: High blood pressure: Adults: 80 mg to 160 mg/daily. Maximum dose 320 mg/day. Heart failure; 40 mg every 12 hours. Adjust the dosage upwards to 80 mg and 160 mg every 12 hours.

Contraindications: Hypersensitivity to any ingredient in the formula. Other angiotensin receptor blockers. In patients with serious liver and/or kidney failure, cirrhosis of the liver, cholestasis of the bile ducts, primary aldosteronism and patients in dialysis. Pregnancy

Side effects: Adverse reactions to valsartan have proven to be mild, temporary and with little effect. The most frequent ones are: CARDIOVASCULAR: Orthostatic effects (hypotension, dizziness), palpitations: NEUROLOGICAL/PSYCHOLOGICAL: occasionally, headache, drowsiness, ataxia. In exceptional cases, insomnia, vertigo, depression, fatigue and neuralgia. RESPIRATORY: occasionally, viral infection, infection of the upper airways, cough, rhinitis, sinusitis, pharyngitis. DIGESTIVE: occasionally, diarrhea, abdominal pain, nausea, dyspepsia. Unusually, gastroenteritis. OSTEOMUSCULAR: occasionally muscle cramps and myalgia. HYPERSENSITIVITY: rarely, angioedema and itching. At the humoral level, slight and occasional  serum increases of creatinine, potassium and bilirubin have been noted. In unusual cases it may be associated with decreased hemoglobin, hematocrit and neutrophils.

Dosage Form: Pills: boxes with 30 coated tablets, 80 mg and 160 mg E.F. 35.863 and E.F. 35.864. Capsules: boxes with 10 and 30 capsules, 80 mg.

BRASARTAN^® CTDN

Ingredients:

• Valsartan 80 mg / Chlorthalidone 12.5 mg

Indications: Second line treatment in patients who fail to respond to monotherapy.

Maximum dose: Valsartan 80 mg – Chlorthalidone 12.5 mg.

Most frequent side effects: VALSARTAN: Cardiovascular disorders: Orthostatic hypotension, nervous system disorders: dizziness. CHLORTHALIDONE: metabolic and electrolytic: hyperglycemia, glycosuria, hyperuricimia, hypochloremic alkalosis, hypercalcemia, hypopotassemia and hyponatremia.

Interactions: Lithium, corticosteroids, amphotericin, hypoglycemiants, amiodarone, anticoagulants, digitalis medications, non-steroidal anti-inflammatory drugs, cyclosporine.

Contraindications: Hypersensitivity to the active ingredients of any of the excipients, pregnancy or suspected pregnancy. Severe liver failure, biliary cirrhosis and cholestasis, anuria, kidney failure, hypopotassemia, hyponatremia, refractory hypercalcemia, gout or uric acid stones.

Dosage Form: Valsartan 80 mg / Chlorthalidone 12.5 mg in packages of 10 and 30 coated tablets. E.F. 42.224/19.

Storage: Store in a dry place at less than 30°C. Keep out of the reach of children.

BREINOX^®

Ingredients:

• Piracetam (2-pyrrolidine acetamide) 400 mg/tab. and 800 mg/tab.

Indications: Treatment of attention and memory disorders that are part of age-related mental deterioration or age-related degenerative disease.

Dosage: Initial: 4.0 gr. per day for one week, followed by 2 gr. per day as a maintenance dose,  split every 8 to 12 hours.

Adverse reactions: May cause agitation, irritability, shaking, nervousness, headache.

Contraindications: Hypersensitivity to the ingredients of the formula. Kidney and/or liver failure. Brain tumors or hemorrhaging.

Warnings: Pregnancy and breastfeeding.

Dosage Form:  400 and 800 mg tablets. E.F. 21.090 y 22.276.

CALCIBON^® D

Ingredients:

• Calcium citrate tetrahydrate 1500 mg (315 mg of elemental calcium).
• Vitamin D_3: 200 IU.

Indications: Calcium and vitamin D3 supplement

Dosage: 1 to 2 tablets per day depending on patient’s needs.

Adverse reactions. In the case of long-term treatment or extremely high doses, there is a possibility of hypercalcemia and hypercalciuria, hypophosphatemia, kidney stones.

Contraindications: Hypersensitivity to the components of the formula, hypervitaminosis, nephrocalsinosis. Prolonged immobility accompanied by hypercalciuria and/or hypercalcemia.

Dosage Form: Bottle with 30 coated tablets. E.F.30.756/11.

CALCIBON^® NATAL FORTE

Ingredients:

• Calcium citrate 950 mg (200 mg of elemental calcium).
• Vitamin D3: 400 IU.
• Folic acid 400 mcg.
• Ferrous fumarate 55.14 mg (18 mg of elemental iron).

Indications: Food supplement with calcium, vitamin D3, folic acid and iron for pregnant women.

How to use: 1 to 2 tablets per day as a food supplement.

Dosage Form: Bottle with 30 coated tablets. A – 100.038.

CALCIBON^® SUPRA, chewable tablets

Ingredients:

• Calcium citrate tetrahydrate 950 mg (equivalent to 200 mg of elemental calcium).
• Vitamin D3: 400 IU.
• Vitamin K1: 60 mcg.
• Magnesium: 50 mg (in the form of magnesium oxide).

Indications: Supplement for the prevention and/or treatment of pre- and postmenopausal bone demineralization and osteoporosis. Treatment of calcium and vitamin D deficiencies.

Dosage: 1 chewable tablet per day.

Warnings and precautions: Administer with care in patients with kidney disease and arteriosclerosis. Large amounts of vitamin K may interfere with the effects of oral anticoagulants such as warfarin. Magnesium supplements should not be given to patients with myasthenia gravis.

Contraindications: Allergy to the ingredients of the formula.

Dosage Form: Bottle with 30 chewable tablets. A 110.122.

CLIMASOY^®

Ingredients:

• Soy isoflavones 100 mg.

Indications: Adjuvant for the treatment of menopause-related discomfort: vasomotor symptoms, sleep disorders, mood changes and prevention of osteoporosis.

Dosage: 1 capsule a day. Do not take for take for a long time and do not exceed the recommended dose.

Warnings and precautions: Pregnancy and breastfeeding. In patients being treated for thyroid problems it may reduce absorption of those medications

Contraindications: Allergy to ingredients of the formula, hormone-dependent tumors, use of anticoagulants such as warfarin

Dosage Form: Bottle with 30 hard capsules. PN: 12-0026.

COLYPAN^®

Ingredients:

• Trimebutine maleate:  200 mg tablets. 300 mg LP tablets.

Indications: Functional colopathy (irritable bowel syndrome) and functional dyspepsia disorders.

Dosage: One 200-mg tablet every 8 hours or one 300-mg tablet every 12 hours for as long as the doctor recommends.

Adverse reactions: Trimebutine is a medication that is very well tolerated and side effects reported are few and mild. Rash in less than 2%, drowsiness in 0.08 %, and very rarely (< 0.01 %) headache, constipation, diarrhea, vomiting, asthenia and dizziness.

Warnings: Do not administer during pregnancy or when pregnancy is suspected or when breastfeeding, unless the doctor were to feel that the risk/benefit ratio favors use.

Dosage Form: 200 mg  tablets E.F. 32.060. 300 mg coated LP tablets E.F. 32.704.

CORAZEM^®

Ingredients:

• Diltiazem hydrochloride in 60- and 90-mg scored tablets.

Indications: Heart failure, mild to moderate hypertension, ischemic cardiomyopathy, angina.

Dosage: Initial dose: 30 mg 4 times a day (before the main meals and before going to bed). The dose must be gradually adjusted every 1 to 2 days based on the patient’s needs until the desired therapeutic response is achieved. The optimum dose varies, although it generally ranges between 180 and 240 mg. per day. The usual dose is 60 or 90 mg 3 times a day.

Contraindications: Sinus node diseases. Second and third degree AV block. Low blood pressure (Systolic pressure less than 90 mmHg). Acute myocardial infarction with heart failure.

Warnings: Caution when using on patients with heart, liver or kidney failure.

Dosage Form: Tablets: Package with 60-mg scored tablets and 90-mg. scored tablets. E.F. 28.460/10 and E.F. 28.489/10.

CORAZEM^® CD

Ingredients:

• Diltiazem hydrochloride in 120- and 180-mg prolonged-release capsules.

Indications: Heart failure, mild to moderate hypertension, ischemic cardiomyopathy, angina.

Dosage: Initial: 120 to 180 mg once a day. Adjust the dose at 2-week intervals. Usual range, 120 to 180 mg per day.

Contraindications: Sinus node diseases. Second and third degree AV block. Hypotension (systolic pressure less than 90 mmHG).

Warnings: Caution when using for patients with heart, liver or kidney failure.

Dosage Form: Capsules: Box containing 10  120-mg and 180-mg prolonged-release capsules. E.F. 28.463/10 and E.F. 28.462/10.

CRISOMET^®

Ingredients:

• Sitagliptin (in the form of sitagliptin phosphate monohydrate 64.25 mg) 50 mg
• Metformin hydrochloride 500 and 850 mg

Indications: Treatment of type 2 diabetes mellitus and as an adjuvant to diet and exercise in patients in whom monotherapy is not effective.

Dosage: Initial dose. 50 mg of sitagliptin – 500 mg. of metformin, twice a day, gradually increasing the dose, depending on the response, up to 50 mg of sitagliptin-1000 mg of metformin twice a day. Maximum dose: Sitagliptin, 100 mg per day; metformin, 2000 mg per day. It must be taken twice a day with meals to prevent adverse gastrointestinal reactions to the metformin. 

Contraindications: Contraindicated in the case of patients who are hypersensitive to the ingredients in the formula, diabetic ketoacidosis, diabetic coma, moderate and severe kidney failure, acute problems that may alter kidney function, such as: dehydration, serious infection, shock, intravenous administration of iodinated contrast agents, acute or chronic disease that can cause tissue hypoxia (lack of oxygen to tissues) such as heart or respiratory failure, recent myocardial infarction, liver failure, among others.

Warnings: Product to be used under strict medical supervision. Not to be taken during pregnancy or when pregnancy is suspected nor while breastfeeding unless the doctor were to feel that the risk/benefit ratio favors use. (See information leaflet inside package).

Precautions and adverse reactions: (See information leaflet inside package).

Interactions with other medications: (See information leaflet inside package).

Dosage forms: Coated tablets: Blister pack with 10, 30 or 60 tablets with the following concentrations:

Crisomet 50 mg – 500 mg coated tablets, E.F.41.808/17 – CPE
Crisomet 50 mg – 850 mg coated tablets, E.F.41.809/17 – CPE

DILUXEN^® 

Ingredients: 

• Pyridostigmine bromide in 60.00 mg tablets

Administration: Oral.

Indications: Treatment of myasthenia gravis.

Posology: Dosage and frequency will depend on the needs of each patient and well as the patient’s clinical response and  tolerance of the medication. Initial dose, 60 mg every 4 to 8 hours followed by gradual increases, if necessary, at intervals of at least 48 hours.

Maximum daily dose: Up to 1.500 mg/day.

Warnings and precautions: Product to be used under strict medical supervision. Not to be administered during pregnancy or when pregnancy is suspected, nor while breastfeeding unless the doctor were to feel that the risk/benefit ratio favors use. Care must used when administering to patients with hypertension and cardiomyopathy or COPD or with serious kidney failure.  Keep out of the reach of children. Do not exceed the recommended dose. This product should not be taken by patients who are lactose or galactose intolerant.

Contraindications: Allergy to any of the ingredients in the formula.  Intestinal and/or urinary tract obstruction. E.F. 42.159/18.

 DOLOMAX 

Ingredients:

• Ketoprofen 100 mg.

Indications: Moderate to severe acute and chronic pain.

Dosage: Oral: 100 mg every  8 hours. Intramuscular: 1 ampoule every 8 or 12 hours depending on the level of pain. Intravenous: 1 ampoule by bolus or infusion.

Contraindications: Allergy to ingredients of the formula.  Pregnancy and breastfeeding.

Dosage Form:  100 mg. enteric-coated tablets. E.F. 28.711. Injection: Package with 1 and 6  100-mg ampoules for  IM use. E.F. 39.129.  Injection: Package with 1 and 6  100-mg ampoules, 5 ml for IV. E.F. 29.824.

DOTRON^®

Ingredients: Each capsule contains:

• Diclofenac potassium 50 mg, excipients.

Indications: Treatment of inflammation and mild to moderate pain, migraines with or without aura, dysmenorrhea and fever.

Dosage: For pain and inflammation: 50 to 100 mg per day split every 12 hours (maximum dose 150 mg/day). For migraine: Single 50 mg dose. Fever: 50 mg every 8 hours. Take together with food.

Adverse reactions:  Most important: Gastrointestinal (pain, irritation, worsening of peptic ulcer disease), hematological (platelet aggregation alterations, thrombocytopenia and other cytopenias), allergic (systemic and skin), and kidney. See information leaflet inside package.

Warnings and precautions: Do not take when pregnant or breastfeeding. Patients with heart or kidney disease. Patients with a history of peptic ulcer disease. Patients with blood disorders. If dengue fever is suspected.

Contraindications: Allergy to ingredients of the formula. Patients with kidney and/or liver failure. Patients with active gastroduodenal ulcer.

Dosage Form: Package with 50 mg capsules. E.F. 38.877/12.

DOTRON^®, suspension

Ingredients: Every 1 ml contains:

• Diclofenac potassium 1.80 mg.

Indications: Treatment of inflammation and mild to moderate pain. Treatment of fever.

Dosage: Children 1 year or older: 0.5 to 2 mg/Kg/day, split in two (every 12 hours) to three doses (every 8 hours). Must be homogenized before use.

Adverse reactions: The most important: Gastrointestinal (pain, irritation, worsening of peptic ulcer disease), hematological (platelet aggregation alterations, thrombocytopenia and other cytopenias), allergic (systemic and skin), and kidney. See information leaflet inside package.

Warnings and precautions: Do not administer when pregnant or breastfeeding. Patients with heart or kidney disease. Patients with a history of peptic ulcer disease. Patients with blood disorders. If dengue fever is suspected.

Contraindications: Allergy to ingredients of the formula. Patients with kidney and/or liver failure. Patients with active gastroduodenal ulcer.

Dosage Form: Bottle containing 120 ml.  E.F. 38.886/11.

FARMA D^®

Ingredients: Each coated tablet contains:

• Dry vitamin D3, 10.00 mg (1,000 IU).
• Dry vitamin D3, 20.00 mg (2,000 IU).

Indications: Prevention and treatment of vitamin D deficiency.

Dosage: Adults: One 1,000 IU or 2,000 IU tablet per day. Maximum dose 4,000 IU per day.

Adverse reactions: Hypercalcemia, hypercalciuria, constipation, flatulence, nausea, epigastric pain, diarrhea, itching, exanthema, hives, headache, vomiting.

Warnings: If pregnant or breastfeeding ask your doctor before taking this product. Do not use if the patient has or has had kidney stones. Do not exceed the recommended dose. Keep out of the reach of children.

Contraindications: Hypersensitivity to ingredients of the formula. Hypercalcemia, hypercalciuria, nephrolithiasis, hypervitaminosis D, tissue calcification (nephrocalcinosis).

Interactions with other medications: See information leaflet inside package.

Dosage Form: Package with 1,000 IU tablets.  E.F.39.856/12 and 2,000 IU E.F. 42.330/19.

FARMACAÍNA^®

Ingredients:

• Lidocaine base.

Indications: Lesions to the oral mucosa and pharynx such as: aphtha, pharyngitis. ENT postoperative pain. As a topical anesthetic for dental procedures that require anesthesia for a short period. When implanting a dental prosthesis, impregnating the entire surface that will be in contact with the new denture is recommended. Prevention and relief of pain during urological procedures in men and women. Treatment of pain caused by some forms of urethritis. Lubricant for surgical instruments.

Dosage Form: Ointment at 5% in 35-mg tube. E.F. 30.870/10

FEMMEX^® ULTRA

Ingredients: Each coated tablet contains:

• Ibuprofen 200 mg.
• Caffeine 30 mg.

Dosage: Adults: One coated tablet (ibuprofen 200 mg – caffeine 30 mg dose) every 6 hours. Maximum dose per day: Ibuprofen, 800 mg; caffeine, 120 mg.

Indications: Painkiller for symptomatic treatment of mild to moderate pain, mild to moderate vascular headaches.

Warnings: If pregnant or breastfeeding, speak to your doctor before using. If the symptoms continue following use, discontinue and speak to your doctor.

Contraindications: Hypersensitivity to any ingredient of the formula. Gastrointestinal hemorrhage, active gastroduodenal ulcer, coagulation disorders and/or treatment with anticoagulants. Recent myocardial infarction. Dengue fever.

Dosage Form: Bottle with coated tablets. E.F. 31.805.

FEMMEXTRA^®    

Ingredients: Each coated tablet contains:

• Ibuprofen 200 mg or 400 mg
• Hyoscine 10 mg or 20 mg.

Indications: Treatment of moderate to severe cramping abdominal pain.

Dosage: 1 tablet every 8 to 12 hours (maximum dose of ibuprofen, 800 mg).

Adverse reactions: Principal reactions:  Nervous system (dizziness, drowsiness, fatigue); ophthalmological (accommodative dysfunction, mydriasis); suppressed secretion of saliva, urination problems and hypersensitivity reactions. See information leaflet inside package

Warnings and precautions: Pregnancy and breastfeeding. Patients with liver and/or kidney failure. High blood pressure and other cardiovascular diseases.

Contraindications: Allergy to ingredients in  the formula. Patients with paralytic ileus or intestinal obstruction. Active gastroduodenal ulcer.

Dosage Form: Package of coated tablets with Ibuprofen 200 mg-Hyoscine 10 mg E.F. 39.949/13.  Package of coated tablets with ibuprofen 400 mg-Hyoscine 20 mg. E.F. 39.350/11.

FITEX^®

Ingredients:

• Tadalafil  tablets  5 and 20 mg.

Indications: Treatment of erectile dysfunction.

Dosage: 5 mg: 5 mg: Adult men: 1 tablet per day continuously. Maximum dose: 1 tablet (5 mg/day). 20 mg.: Adult men: 1 tablet 30 minutes before sexual activity, with any meal. Maximum dose: 1 tablet (20 mg.). Wait 24 to 36 hours before taking again.

Contraindications: Hypersensitivity to tadalafil or any ingredients of the formula.  Patients with heart diseases when sexual activity is contraindicated. Patients undergoing treatment with any form of organic nitrate, such as nitric oxide or nitrates in any of their pharmaceutical forms. Patients with severe kidney and/or liver disease. Those under the age of 18 years and women. This product should not be taken by patients who are lactose or galactose intolerant.

Dosage Form: Tablets: Package with 30  5-mg coated tablets; package with  1 and 10 20-mg coated tablets; package with 1 and 10  20-mg  orally disintegrating tablets. E.F. 39.597/12, E.F.38.634/11 and  E.F.40.783/14.

FLEBOSMIN^®

Ingredients: Each coated tablet contains:

• Purified flavonoid fraction (Equivalent to Diosmin 450 mg / Hesperidin 50 mg) 500 mg.
• Excipients as necessary.

Indications: Treatment of the symptoms of chronic peripheral venous insufficiency and hemorrhoids.

Dosage: Chronic venous insufficiency: 2 tablets per day (1,000 mg per day), split into 2 doses. Hermorrhoid crisis: 2 tablets (1,000 mg) every 8 hours for 4 days, followed by 2 tablets (1,000 mg) every 12 hours over the following 3 days.

Contraindications: Allergy to the ingredients of the formula.

Warnings: Should be administered with care under medical supervision. Do not administer during pregnancy or when pregnancy is suspected, or when breastfeeding. If there is no relief of the hermorrhoidal disorder after 15 days, speak to your doctor. Not to be administered together with antiacids or extremely alkaline foods as they can reduce absorption.

Dosage Form: Package containing 30  500-mg coated tablets. E.F. 34.479/17.

FRICSOL^®

Ingredients: Gel: Every 100 g contains:

• Methyl salicylate 10 g
• Menthol 10 g
• Excipients: Eucalyptus oil, ethyl alcohol, cetyl alcohol, cutin MD, emulgin B1, emulgin B2, propylparaben, methylparaben, isopropyl myristate, carbomer 940, triethanomaline, glycerin, water, amount necessary.

Indications: Topical analgesic. Rubefacient for pain in muscles or joints. Back pain, lumbago, neuralgia and sprains.

Precautiones: For external use only. Avoid contact with eyes and mucosal tissue; in case of contact, rinse immediately with plenty of clean water. Do not apply over large areas of the skin. Do not apply to skin that is irritated or to wounds. In the case of sprains, apply without massaging.

Contraindications: Hypersensitivity to an ingredient in the formula. This product should not be used by people who are allergic to acetylsalicylic acid or other salicylates, patients with asthma of who have a prediposition to laryngial spasms, convulsions.

Dosage Form:  Collapsible aluminum tube with 30 g. E.F. 29.036/09.

HIDROTEN^®

Ingredients :

• Chlorthalidone 12.5 mg.

Indications: Treatment of  arterial hypertension and isolated systolic hypertension

Dosage: Adult: 12.5 to 25 mg per day.

Contraindications: Hypersensitivity to any ingredient of the formula. It should not be administered to patients with anuria, kidney or liver failure, hypopotassemia, refractory hypercalcemia, hyponatremia,  hypomagnesemia, hypophosphatemia, hyperuricemia or lupus erythematosus, a history of gout or uric acid  stones.

Warnings: Chlorthalidone must be administered with extreme caution in the case of diabetic patients being treated with hypoglycemic medications or insulin and, if it is  necessary, adjusting the doses of the hypoglycemic medications and/or insulin. Chlorthalidone may increase the effects of digitalis poisoning as well as low blood pressure due to other blood pressure medications

Dosage Form: Tablets: Package with 12.5 mg tablets x 30 capsules. E.F. 39.5220/12.

KALMAX^® COMPOSITUM

Ingredients: Each chewable tablet contains:

• Famotidine: 10 mg.
• Magnesium hydroxide 165 mg.
• Calcium carbonate 800 mg. Excip. (sorbitol, sucralose and others) amount necessary.

Indications: Symptomatic relief of heartburn.

Dosage: 1 chewable tablet every 12 hours, preferably after meals. Chew the tablet until it dissolves completely in your mouth then swallow with a glass of water. The dose may be increased as recommended by the doctor.

Contraindications: Hypersensitivity to any H2 blockers. Severe liver and/or kidney failure.

Adverse reactions: Very infrequent: Constipation, diarrhea, nausea, dizziness, headache, rash, hydroelectrolytic disorders, liquid or fluid retention, hypercalcemia and hypermagnesemia.

Warnings: Do not administer during pregnancy or when pregnancy is suspected nor when breastfeeding unless the doctor were to feel that the risk/benefit ratio favors use. It should not be given to patients with severe liver and/or kidney failure. Not recommended for those under 18 years old. Do not administer to patients who abuse alcohol or who are undergoing regular treatment with diphenylhydantoin, warfarin and theophylline.

Dosage Form: Mint-flavored chewable tablets. E.F. 35.709.

KIDCAL^®, suspension

Ingredients: Every 5 ml contains:

• Light calcium carbonate 750 mg (300 mg calcium ion).
• Vitamin D3 crystals 0.0025 mg (100 IU).
• Zinc oxide 9.335 mg (7.5 mg zinc ion).

Indications: Food based on calcium, vitamin D3 and zinc.

How to use:  Children over 2 years: 1 to 2 teaspoons (5 to 10 ml) per day. The dose may be increased if ordered by doctor. To be taken in addition to a well-balanced diet.

Contraindications: Allergy to the ingredients of the formula. Active gastroduodenal disease. Kidney stones.

Dosage Form:  180 ml. bottle of tutti-frutti flavored suspension. A-84.542.

LIPACOMB^®

Ingredients:

• Each tablet contains simvastatin 20 mg and ezetimibe 10 mg.

Indications: Treatment of primary hypercholesterolemia. Homozygous familial hypercholesterolemia.

Dosage: One (1) tablet per day at the concentration prescribed by the doctor. Maximum dose, 80 mg of simvastatin/10 mg ezetimibe per day.

Contraindications: Hypersensitivity to an ingredient of the formula. Do not administer during pregnancy or when pregnancy is suspected. Patients with acute liver and/or kidney failure or persistent unexplained increase in the serum transaminases. Pediatric age.

Dosage Form: Tablets: Package of 20/10 mg. tablets. E.F.37.386 

MACRODANTINA^®    

Ingredients:

• Nitrofurantoin macrocrystals in 50-mg capsules.

Indications: Treatment of  uncomplicated lower urinary tract infections caused by nitrofurantoin-sensitive germs.

Dosage: 50 to 100 mg, four times a day, with meals and before going to bed.

Contraindications: Anuria, oliguria or advanced kidney failure. Full-term pregnant patients and babies under 1 month old for possible hemolytic anemia due to immature enzyme systems of the fetus or the newborn.

Dosage Form: Capsules: Package with 50-mg capsules x 30 capsules. E.F. 16.065/09.

MAGALEX^®

Ingredients:

• Magnesium citrate 622.28 mg (equivalent to 100 mg of elemental magnesium).

Indications: Magnesium citrate food supplement in capsules. Gluten free.

How to use: Take one (1) capsule a day. No more than four (4) capsules per day, preferably with meals.

Recommendations: Do not exceed the recommended dose. Keep out of the reach of children.

Storage: Store at room temperature below 30°C.

Dosage Form: Bottle with 30 and 60 capsules. A-120.879.

NEBLUM®.

Composition: Each coated tablet contains:

24.3mg Sacubitril / 25.7mg valsartan.

Indications: Treatment of heart failure (NYHA class II-IV) in patients with systolic dysfunction.

Dosage: Initial dose 50 mg every 12 hours in patients not taking renin angiotensin aldosterone system inhibitors [angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs)]. In case of taking an angiotensin-converting enzyme inhibitor, Neblum should be started 36 hours after discontinuation, to avoid safety problems.

If necessary, the initial dose should be doubled every 2 to 4 weeks, with a maximum dose of 200 mg every 12 hours.

Adverse reactions: hypotension, diarrhea, fatigue, nausea, myalgia, cough, dizziness, hyperkalemia.

Warnings and Precautions: Pregnancy and lactation. Should not be co-administered with an ARB or ACEI. Patients with moderate to severe hepatic insufficiency. Water-electrolyte imbalance; before starting treatment, sodium loss should be corrected.

Presentation:

Authorized by the M.P.P.S under No.:

NEBLUM 24.3 mg- 25.7 mg. 30 coated tablets E.F.42.653/21;

NEBLUM 48.6 mg- 51.4 mg. 30 coated tablets E.F.42.654/21;NEBLUM 97.2 mg -102.8 mg. 30 coated tablets. E. F.42.655/21

NEURIXA^®

Ingredients: Each capsule contains:

• Pregabalin  75 and 150 mg.

Indications: Neuropathic pain. Fibromyalgia. Anticonvulsant in patients who do not respond to treatment with other anticonvulsants.

Dosage:  As prescribed by the doctor.

Adverse reactions: Abdominal pain, dizziness, headache, peripheral edema. High blood pressure, syncope. Neutropenia. Ataxia, confusion, lack of coordination, vertigo, dysarthrea, drowsiness or insomnia. Others: See information leaflet inside package.

Warning and precautions: Pregnancy and breastfeeding. Cessation of this medication must be gradual and under the supervision of a doctor. If treatment were to be stopped  suddenly, there is a risk that seizures or the epileptic condition (in patients being treated for epilepsy) could resume.

Contraindications: Hypersensitivity to an ingredient in the formula. Pregnancy and breatfeeding, arterial hypertension.

Dosage Form: Package with 75 mg and 150 mg  capsules x 14 capsules .E.F. 38.421/10, E.F. 38.422/10.

NIFELAN^® CD     

Ingredients:

• Tablets with 30 mg of nifedipine.

Indications: Treatment of mild, moderate and severe hypertension. Treatment of chronic stable angina (stress angina), including prinzmetal angina or variant angina.

Dosage: 30 to 60 mg/day.

Warnings: Nifedipine may cause mild to moderate peripheral edema, depending on the dosage. This edema is a localized phenomenon associated with vasodilation of the arterioles and small blood vessels, not with left ventricular dysfunction of general fluid retention.

Interactions with other medications: Non-steroidal anti-inflammatory drugs (NSAIDs), beta-andrenergic blockers, cimetidine, anticonvulsants such as phenytoin and carbamazepine, digoxin and quinidine (control plasma levels), other high blood pressure medications, inhalation anesthetics, estrogens, lithium.

Dosage Form: Tablets: Package with 30-mg  tablets. E.F. 35.311.

NINAZO^®, drops for adults.

Ingredients: Every 1 ml contains:

• Naphazoline nitrate 1 mg. Excip.: Isotonic solution with a pH of approximately 6.2.

Indications: Nasal decongestant.

Dosage: Recommended dose: 2 drops in each nostril 3 times per day.

Warnings: Pregnancy or breastfeeding (speak to your doctor before using this product). If the symptoms persist when using this medication, stop use and speak to your doctor. Prolonged use of this product can cause nervousness, restlestness and insomnia. Do not exceed the recommended dose. Keep out of the reach of children

Dosage Form: Plastic bottle with 15 ml. E.F. 8.474/10.

NINAZO^®, drops for children.

Ingredients: Every 1 ml contains:

• Naphazoline nitrate 0.5 mg. Excip.: Isotonic solution with a pH of approximately 6.2.

Indications: Nasal decongestant.

Dosage: Children over 6 years: 2 drops in each nostril 3 times a day.

Contraindications: Hypersensitivity to any ingredient in the formula. Glaucoma. Children under 6 years of age.

Dosage Form: Plastic bottle with 15 ml. E.F. 8.473/12.

NORMIX^®

Ingredients: Each coated tablet contains:

• Rifaximin: 200 mg. Excip. amount necessary.

Indications: Treatment of gastrointestinal infections caused by rifaximin-sensitive enteropathogens. Pre- and post-operative prophylaxis for infections following colon surgery. Reduction of intestinal bacterial flora in patients with liver failure (hyperammonemia).

Dosage: 600 to 800 mg per day, split into two or three doses, for 5 to 7 days.

Adverse reactions: General: Headache, fever. Gastrointestinal: Flatulence, abdominal pain, rectal tenesmus, nausea, constipation, vomiting. Other: Allergic skin reaction.

Dosage Form: Coated tablets: Box of 12 in bubble pack. E.F. 36.695.

NOTOLAC^®

Ingredients: Each tablet contains:

• Keterolac tromethamine.

Indications: Treatment of  inflammation and/or mild to moderate pain. Short-term treatment for moderate to severe pain following surgery or trauma.

Dosage: Initial dose: 10-20 mg. Maintenance: 10 mg every 6 to 8 hours or 20 mg every 12 hours. Maximum dose, 40 mg/day. Do not use for more than 5 days in a row.

Adverse effects: Dyspepsia, gastrointestinal pain and nausea. Less frequently: diarrhea, dizziness.

Warnings and precautions: History of peptic ulcer, kidney failure, liver disorders, coagulation disorders, geriatric patients (>65 years), fluid retention, cardiac decompensation or arterial hypertension. Maximum period to be taken: 5 days. See information leaflet inside package.

Contraindications: Allergic response to aspirin or any other NSAID.  Pregnancy and breastfeeding.

Dosage Form: 30 mg sublingual tablets x 4,  20-mg tablets x 10.

PIOKILIN^®

Ingredients:

Dimethicone at 4%, cyclomethicone.

How to use:  Apply the lotion evenly on dry hair and allow to dry naturally. Leave it on for at least 8 hours or overnight. Wash hair with usual shampoo and rinse with plenty of water. Apply again 7 days after the first application.

Warnings: This product must not be ingested. Avoid contact with eyes; if it does get into eyes, rinse with plenty of water. In the event of an unfavorable reaction, stop using and speak to a doctor. Keep out of the reach of children.

Precautions:  For external use only. Nº NSO-PC-D-55.070-VE.

REGULIP^®

Ingredients:

• Rosuvastatin calcium in 10-mg tablets.

Indications: Simple or mixed dyslipidemia, primary or secondary, when response to diet and other measures prove not to be enough.

Dosage: From 5 to 40 mg per day.

Contraindications: Hypersensitivity to rosuvastatin or any other ingredient in the formula. Do not administer during pregnancy or when pregnancy is suspected. Patients with liver and/or kidney dysfunction. Children under 12 years of age.

Warnings: Alterations to kidney function have been found with the administration of this product, therefore, transaminases, creatine kinase (CK),  bilirubin total and fractionated, should be monitored. If the concentration of transaminases increases more that 3 times the upper limit, treatment must be suspended. Levels of CK must be measured in patients with symptoms that suggest myopathy.

Dosage Form: Tablets: Box with 10-mg tablets.  E.F. 39.374/11.

RINARIS^®

Ingredients:

• Each tablet contains loratadine 5 mg and pseudoephedrine 60 mg.

Indications: Initial treatment of acute symptoms caused by allergic rhinitis.

Dosage: Dose recommended for children over 12 years and adults: 1 tablet every 12 hours for no more than 3 days.

Contraindications: Hypersensitivity to ingredients of the formula. Glaucoma, pyloric stenosis, urinary retention, cardiovascular diseases including hypertension, diabetes mellitus.

Warnings: This product may cause drowsiness, therefore when taking it patients should avoid activities requiring coordination and mental alertness.

Dosage Form: Tablets: Box with coated tablets. E.F. 35.116.

RINOLAST^®

Ingredients:

• Fexofenadine hydrochloride in  120-mg tablets.

Indications: Relief of the symptoms associated with congestion in the upper respiratory system such as allergic rhinitis, with sneezing, runny nose, nasal congestion and allergic skin reactions, such as atopic dermatitis.

Dosage:  Adults and children over 12 years old: 1 tablet per day.

Dosage Form: Tablets: Box with 10 tablets 120 mg each. E.F. 32.231/09

RINOLAST^® D 

Ingredients:

• Tablet:  Fexofenadine hydrochloride, 60 mg and pseudoephedrine hydrochloride, 60 mg. tablets.
• Suspension: Every 5 ml contains 30 mg of fexofenadine hydrochloride and 30 mg of pseudoephedrine hydrochloride

Indications: Allergic rhinitis and nasal decongestant.

Dosage: Children from 6 to 11 years: 1 teaspoon (5 ml) every 12 hours. Adults and children over 12 years: 2 teaspoons with 5 ml each every 12 hours or 1 tablet every 12 hours.

Dosage Form: Tablets: Box with 10 tablets. E.F. 32.234/09. Suspension: Bottle with 120 ml. E.F 32.233/09.

SENOKOT^® CON DOCUSATO

Ingredients: Each tablet contains:

• Sennosids A and B from Cassia acutifolia 8.6 mg.
• Docusate sodium 50 mg.

Indications: Relief of occasional constipation. For soft, comfortable stools.

Dosage: Adults: 1 tablet per day, preferably at night before going to bed, for a comfortable and predictable bowel movement the following morning. Maximum dose: 4 tablets per day. Elderly or weak patients: half the adult dose. Children from 6 to 11 years: begin with ½ tablet per day. Maximum dose: 2 tablets per day, preferably at night before going to bed. The dose must be adjusted gradually depending on the patient’s response without exceeding the maximum recommended dose.

Adverse effects: Rarely, and particularly in case of an overdose: abdominal cramps, diarrhea, nausea, abdominal bloating and flatulence.

Contraindications: Acute surgical abdomen, fecal impaction, intestinal obstruction. Precautions: Do not use for more than one week unless indicated by the doctor. Avoid using this product together with mineral-oil laxatives since it could cause increased systemic absorption of the latter.

Warnings: Do not administer during pregnancy or when pregnancy is suspected. Do not use laxatives in the case of abdominal pain, nausea and vomiting.

Dosage Form: Tablets.  P.N.97-0343.

STAMYL^® FORTE

Ingredients: Each coated tablet contains:

• Pancreatin 300 mg.
• Simeticone 100 mg.

Indications: Temporary and symptomatic relief of digestion disorders, antiflatulent.

Dosage: 1 tablet before or immediately after meals. Do not chew the tablets.

Warnings: Pregnancy and breastfeeding. If there is no improvement, speak to your doctor. Do not administer to children under 12 years of age.

Contraindications: Allergy to the ingredients of the formula. Gastrointestinal stenosis.

Dosage Form: Coated tablets. E.F. 40.123/13.

TAPAZOL^®

Ingredients : Each tablet contains:

• 5 mg of thiamazole (methimazole).

Indications: Treatment of hyperthyroidism.

Dosage: Initial dose: mild hyperthyroidism: 15 mg per day. Moderately severe hyperthyroidism: 30 to 40 mg per day. Severe hyperthyroidism: 60 mg per day. Maintenance dose: 5 to 15 mg per day with a doctor’s prescription.

Adverse reactions: Hives, nausea, vomiting, arthralgia, headache, vertigo. More severe but unusual reactions: Agranulocytosis, hepatitis, drug-induced lupus. Nephritis. Hypoprothrombinemia. Use with caution, see information leaflet inside package.

Contraindications: Allergy to methimazole. Pregnancy and breastfeeding (it is excreted through the mother’s milk).

Dosage Form:  5 mg. tablets. E.F. 2.995/11.

TERACEZINC^®

Ingredients: Each capsule contains:

• Vitamin C 513 mg (500 mg  of ascorbic acid).
• Zinc sulfate 33 mg (7.5 mg of zinc).
• Excipients: Lactose monohydrate  123.90 mg, others amount necessary.

Indications: Treatment of vitamin C and zinc deficiency

Dosage: 1 to 2 capsules per day. Maximum dose 4g per day of vitamin C. Do not take for more than 60 days.

Adverse reactions: At high doses it can cause diarrhea, headache, gastralgia. It may favor hyperoxaluria and aggravate kidney stones.

Warnings and precautions: More than 4.0 gr of vitamin C per day can lead to or aggravate kidney stones. Pregnancy and breastfeeding.

Contraindications: Allergy to the ingredients of the formula. High uric acid level.

Dosage Form: Package with 24 and 60 capsules. E.F. 33.736/11.

TERAGRIP Forte^®

Ingredients:

• Acetaminofen 650 mg, caffeine 20 mg, chlorpheniramine maleate 2 mg, aspartame 175 mg, mannitol 2700 mg, cane suger 5830.875 mg, others necessary amount.

Indications: Relief of the sypmtoms of the common cold.

Dosage: 1 packet every 6 to 8 hours, dissolved in one cup of hot or cold water.

Warnings: If symptoms persist for more than 3 days, suspend treatment and speak to your doctor. It may cause drowsiness; when taking it patients should avoid activities requiring coordination and mental alertness; refrain from drinking alcohol or taking sedatives when taking this medication. Do not administer to children under 12 years. Pregnancy or breastfeeding: speak to your doctor.

Dosage Form: Packets: boxes of 6  E.F. 35.931.

TERAGRIP Forte noche^®

Ingredients:

• Acetaminofen 650 mg, chlorpheniramine maleate  4 mg, aspartame 175 mg, cane sugar 6046.87 mg, others amount necessary.

Indications: Relief of the sypmtoms of the common cold.

Dosage: 1 packet every 6  hours, dissolved in one cup of water.

Warnings: If symptoms persist for more than 3 days, suspend treatment and speak to your doctor. It may cause drowsiness; when taking it patients should avoid activities requiring coordination and mental alertness; refrain from drinking alcohol or taking sedatives when taking this medication. Do not administer to children under 12 years. Pregnancy or breastfeeding: speak to your doctor.

Dosage Form: Packets: boxes of 6  E.F. 34.017.

TERAGRIP Jarabe

Ingredients:

Cada 5 ml contains:

• Acetaminofen 125 mg.
• Chlorpheniramine maleate  1 mg.
• Cane sugar       2.615 mg.
• Excipientes     amount necessary.

Indications: Relief of the symptoms of the common cold.

Dosage: Children from 7 to 12 years: 2 teaspoons (10 ml) every 6 hours.

Contraindications: Allergy to the ingredients of the formula

Warnings: If symptoms persist when taking this medication, suspend treatment and speak to your doctor. It may cause drowsiness; when taking it patients should avoid activities requiring coordination and mental alertness. Keep out of the reach of children. Do not exceed the recommended dose.

Dosage Form: Syrup: bottle with 120 ml (grape flavored). E.F. 28.216.

TERAGRIP^® Supra
Ingredients:

• Tablets: Acetaminofen 650 mg, pseudoephedrine hydrochloride 30 mg, dextromethorphan hydrobromide 15 mg, chlorpheniramine maleate 4 mg, excipients amount necessary.

Indications: Relief of the sypmtoms of the common cold.

Dosage: Adults and children over 12 years: 1 tablet every 6 hours.

Warnings: If symptoms persist for more than 3 days, suspend treatment and speak to your doctor. It may cause drowsiness; when taking it patients should avoid activities requiring coordination and mental alertness; refrain from drinking alcohol or taking sedatives when taking this medication. For patients with arterial hypertension, thyroid or heart disease, speak to the doctor before taking. Administration in extremely high doses over a long period of time may cause serious liver or kidney lesions. Pregnancy and breastfeeding: speak to your doctor.

Dosage Form: Tablets: Packages of 10  E.F. 37.166.

TERATOSIL^®

Ingredients :

• Every 5 ml of syrup contains:  Dry extract of ivy leaves (Hedera hélix) 0.035 g, sorbitol solution 70% 2.750 g.

Indications: Adjuvant for fluidization of bronchial secretions.

Dosage: Children from 2 to 5 years: 2.5 m. (1/2 teaspoon) 3 times a day. Children from 6 to 12 years: 5 ml (1 teaspoon) 3 times a day. Children 12 years and over and adults: 7.5 (1-1/2 teaspoons) 3 times a day.

Contraindications: Allergy to the ingredients of the formula.

Dosage Form: Syrup: Plastic bottle with 120 ml,  with dosing cup included. P.N. 12.0027.

TONERVOL^®

Ingredients:

• Nebivolol  5 mg.

Indications:

• Treatment of essential  arterial hypertension.
• Treatment of stable chronic heart failure.

Dosage:

• Treatment of essential arterial  hypertension: Adults: 5 mg per day.
• Treatment of stable chronic heart failure: Adults: Initial dose: 1.25 mg for the first week, increasing the dose to 2.5 mg during the second week depending  on patient’s tolerance to the medication.

Maximum Dose:

Treatment of essential arterial hypertension: Adults: 5 mg per day.

Treatment of stable chronic heart failure: 10 mg per day.

Dose for patients over 65: Begin with 2.5 mg

Moat frequent side effects: Constipation, nausea, diarrhea, headache, vertigo, paresthesia, dyspnea, weariness.

Interactions: Paroxetine, fluoxetine, thioridazine, class I antiarrihythmic drugs, calcium channel blockers (verapamil/diltiazem), and centrally acting hypertensives.

Contraindications: Hypersensitivity to the ingredients of the formula, severe bradycardia, AV block, cardiogenic shock, decompensated heart failure, sinus node dysfunction and severe liver failure. Use in pregnant women has not been evaluated.

Warnings: Avoid use during pregnancy or when breastfeeding.

Dosage Form: 5-mg scored tablets x 10, 30, 50 tablets.

Storage: Store in a dry place at a temperature below 30°C. Keep out of the reach of children.

ULCON^®

ULCON® 1 g / 5 mL SUSPENSION

Ingredients: Every 5 mL of suspension contains:
Sucralfate (Basic aluminum salt of sulfated sucrose) 1.00 g.
Excipients:
Sodium saccharin 0.0075 g.
Sodium cyclamate 0.03 g.
Others, amount necessary.

ULCON® 1 g TABLETS

Ingredients: Each tablet contains:
Sucralfate (Basic aluminum salt of sulfated sucrose) 1.00 g.
Excipients:
Corn starch 0.0187 g.
Others, amount necessary.

Route of administration: Oral.

Indications: Treatment of gastroduodenal ulcer and gastritis.

Posology: Dose: Adults: 1 g every 6 hours on an empty stomach. Treatment should be continued for 4 to 8 weeks, unless there is earlier endoscopic or X-ray proof of a cure.

Maximum daily dose: The usual recommended dose (4 g per day).

Dose in patients with kidney failure, liver failure and the elderly: No need for an adjustment to the dosage has been described.

How to use: In all forms it must be taken on an empty stomach (1  hour before or 2 hours after a meal). It should be taken 1 hour before each meal and at night before going to bed. Tablets: Take orally with water. Suspension: Take orally, drinking ¼ of ½ glass of water after each dose. Shake before using to homogenize the suspension.

Adverse effects: Frequency unknown: anemia, vomiting, gastric discomfort, indigestion, flatulence, diarrhea, headache, dizziness, drowsiness, insomnia, encephalopathy, back pain, osteodystrophy, osteomalacia, vertigo, anaphylactic reaction (including itching, rash, angioedema, rhinitis, dyspnea, laryngeal spasm and bronchospams). Frequent: constipation. Infrequent: dry mouth, nausea. Rare: feeling of full stomach, bezoars, rash.

Warnings and precautions: Product to be used with caution under the supervision of a doctor. Do not administer during pregnancy or when pregnancy is suspected, or when breastfeeding unless prescribed by the doctor. Although systemic absorption of aluminum associated with the use of sucralfate is very low, in patients with severe kidney failure it could lead to accumulation and cause toxicity. In this regard, there have been reports of cases of aluminum osteodystrophy, osteomalacia and encephalopathy. In view of this, this medication should be used with extreme caution in these patients and the serum level of aluminum should be checked regularly. Cases of bezoars in hospitalized patients treated with sulcrafate for the prevention of stress ulcers have been reported. The documented cases mainly involve critically ill patients in intensive-care units who also have underlying conditions causing a predisposition to the formation of a bezoars (slowing down of gastric emptying due to surgery, medication therapy or diseases that reduce intestinal motility) or who are receiving enteral feeding through a nasogastric tube. Efficacy and safety for children under 14 years of age has not been determined.

Keep out of the reach of children. Do not exceed the prescribed dose.

Contraindications: Allergy to any of the ingredients in the formula.

Interactions: Sucralfate may reduce (by absorption) the bioavailability of  orally –administered medications (such as: fluoroquinolones, tetracyclines, theophylline, phenytoin, digoxin, warfarin, ketoconazole, levothyroxine, quinidine, cimetidine and H2 blockers) and, therefore, jeopardize the therapeutic efficacy of the latter. To prevent this, sucrafalate and these medications should be administered at least 2 hours apart. The concomitant use of sucrafalate and antacids containing aluminum could foster corporal accumulation of the cation and lead to toxicity.

Storage: Store at room temperature at less than 30º C.

FOR SALE WITH A DOCTOR’S PRESCRIPTION.
Manufactured and distributed in Venezuela by LABORATORIOS FARMA S.A. RIF: J-00013393-0
AO/nf
September 7, 2021

UROCIT^®

Ingredients:

• Each tablet contains potassium citrate 1080 mEq (10 mEq).

Indications: Urinary alkalinizer in patients with uric-acid kidney stones. Treatment of calcium-oxalate kidney stones.

Dosage: In patients with severe hypocitraturia (urine citrate below 150 mg per day), treatment should begin with a dose of 60 mEq perday (20 mEq 3 times a day or 15 mEq 4 times a day with meals or 30 minutes after meals or with a snack at bedtime). In patients with mild to moderate hypocitraturia (>150 mg per day), the initial dose of Urocit should be 30 mEq per day (10 mEq 3 times a day with meals). Maximum dose, 100 mEq per day.

Contraindications: Adrenal failure, kidney failure, respiratory or metabolic alkalosis, intestinal obstruction, active gastric ulcer.

Adverse effects: May cause mild gastrointestinal disorders such as dyspepsia, nausea, vomiting, diarrhea, which can be eased by administering with meals.

Warnings: Do not administer during pregnancy or when pregnancy is suspected, nor when breastfeeding. The active ingredient is released from the wax matrix to work. The matrix is an inert vehicle and can be excreted without causing changes in the stool.

Dosage Form: Tablets: Bottle with 100 prolonged-release tablets with 10 mEq each. E.F. 37.073.

VALPRON^®, tablets

Ingredients: Each tablet  contains:

• Valproic acid 500 mg.

Indications: Anticonvulsant for the prophylactic treatment of generalized epileptic seizures (grand mal and petit mal) and partial seizures. Epilepsy and mania, prevention of migraine crises.

Dosage: Adults: prophylactic treatment for epileptic seizures: 500 to 1000 mg per day. Epilepsy and mania: 1000 to 3000 mg per day. Migraine prophylaxis: 500 to 1000 mg per day. With a doctor’s prescription.

Adverse effects: Toxic hepatitis, thrombocytopenia, ataxia, dysarthrea, headache, nausea, weakness, anorexia, diarrhea or constipation. 

Warnings: Product must be used with care. Administer only under strict medical supervision. In the event of loss of appetite, dizziness, general weakness, drowsiness or any other symptom, speak to your doctor immediately. Valproic acid is a hepatotoxic, mainly if given to children under 2 years old who are taking several anticonvulsive medications due to refractory seizures and/or who have congenital metabolic disorders. Toxic hepatitits in older childrn and adults is not frequently found at the recommended dosage. The patient must absolutely be kept under close clinical and laboratory observation, especially during the early months of the treatment. Any alteration in laboratory results for assessing liver function, as well as symptoms such as anorexia, muscular weakness, drowsiness, dizziness, should lead to immediate replacement of valproic acid with other anticonvulsive treatments.

Precautions: An increase in plasma levels of phenobarbitol and variable alterations of the plasma levels of diphenylhydantoin sodium has been observed; therefore any association between this medication and valproic acid must be determined on an individual basis and adjusted to the clinical needs of each patient. Avoid administering together with clonazepam.

Dosage Form: 500-mg tablets E.F. 23.401/10.

VALPRON^®, solution

Ingredients: Sodium valproate.

Indications: Anticonvulsant for the prophylactic treatment of generalized epileptic seizures (grand mal and petit mal) and partial seizures. Epilepsy and mania.

Dosage: Children: Prophylactic treatment for epileptic seizures: 15 to 30 mg per kilo per day. Epilepsy and mania: 15 to 60 mg per kilo per day. With a doctor’s prescription

CONTRAINDICATIONS, WARNINGS AND SIDE EFFECTS: See  VALPRON 500 mg  tablets.

Dosage Form: Solution in drops: 30-mL bottle with measured dropper, with 200 mg/mL. E.F.21.902/10.

VENOLEG^®

Ingredients:

• Centella asiatica, equivalent to asiaticosides 40%, aescin, demineralized water.

Indications: Symptomatic relief of tired-leg syndrome.

Dosage: Apply the gel once or twice a day ,massaging feet and legs in an upward motion for a few minutes until fully absorbed.

Warnings: Do not ingest this product. In the event of an unfavorable reaction, stop using. If the reaction persisists, speak to your doctor. For external use only, avoid contact with eyes and mucosa, irritated skin or open wounds; if it does occur, rinse well with plenty of clean water.

Dosage Form: Tube with 60 g. of refreshing gel refrescante NSO-PC-B-55.449VE.